Risk of febrile seizures after first dose of measles–mumps–rubella–varicella vaccine: a population-based cohort study

From CMAJ June 9, 2014

Risk of febrile seizures after first dose of measles–mumps–rubella–varicella vaccine: a population-based cohort study

Background: The combination measles–mumps–rubella–varicella (MMRV) vaccine currently used in Canada (Priorix-Tetra) may increase the risk of febrile seizures relative to the separate vaccines (MMR and varicella) previously administered. We determined the risk of febrile seizure after the first dose of MMRV, as well as any additional risk for children at high risk for seizures because of pre-existing medical conditions.

http://www.cmaj.ca/content/early/2014/06/09/cmaj.140078